df[['new_column_1_name', 'new_column_2_name']] = pd.DataFrame([[np.nan, 'word']], index=df.index)
import pandas as pd
import numpy as np
df = pd.DataFrame({
'col_1': [0, 1, 2, 3],
'col_2': [4, 5, 6, 7]
})
print(df)
col_1 col_2
0 0 4
1 1 5
2 2 6
3 3 7
df[['new_col_1', 'new_col_2', 'new_col_3']] = pd.DataFrame([[np.nan, 42, 'wow']], index=df.index)
print(df)
col_1 col_2 new_col_1 new_col_2 new_col_3
0 0 4 NaN 42 wow
1 1 5 NaN 42 wow
2 2 6 NaN 42 wow
3 3 7 NaN 42 wow
df['new_col_1'] = np.nan
df['new_col_2'] = 42
df['new_col_3'] = 'wow'