1# python 3.x
2import pandas as pd
3import numpy as np
4
5df = pd.DataFrame(data=np.random.randint(0, 10, (6,4)))
6
7df.columns=["a", "b", "c", "d"]
8print(df)
1Cov = pd.read_csv("path/to/file.txt", sep='\t')
2Frame=pd.DataFrame(Cov.values, columns = ["Sequence", "Start", "End", "Coverage"])
3Frame.to_csv("path/to/file.txt", sep='\t')